Regenerative Therapies for
Pain Relief and Longevity

We utilize the healing power of nature by recognizing and promoting an inherent self-healing process and removing any obstacles prohibiting the body to heal. The impact of disease and degeneration is limited while restoring the body through the integration of cutting-edge modern medicine, science, and technology.

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Dr. Squires

These cell-based therapies use advanced scientific techniques in the treatment of degenerative disease, orthopedic injuries, and joint conditions. The body’s natural immune response is stimulated to promote healing and repair by encouraging growth factors, fibroblast, immune cells, stem cells, and collagen-building precursors to the injured area.

The goal of Regenerative Medicine / Orthobiologic Therapies is finding equilibrium between repair and breakdown in the body. The body has constant regenerative processes, based on the constant turnover of cells in all tissues of the body. Osteoarthritis, tendinopathies, and ligamentous tears that do not heal are examples of when the breakdown outweighs the repair.

1. Orthobiologic Pain Solutions, Natural and Regenerative Medicine

Your neck, back, shoulders, hips, knees, and ankles are connected, and so is your pain and inflammation.

Our approach brings together a holistic treatment of all the factors contributing to your chronic inflammation and pain. Personalizing treatment to the factors most impacting your source of pain.

Dr. Squires explains more here.

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2. Stem Cell Therapies

Autologous stem cell therapies are cell-based orthopedic treatments that can offer a less invasive, alternative to surgery for individuals suffering from joint pain. They can also be used in cases where surgery is not recommended but you are suffering from chronic pain and lack of function.

Autologous meaning from your own body are found in bone marrow, blood, and adipose tissue. These cells can derive cartilage, bone, muscle, tendon, and ligaments.

Autologous stem cells are harvested and processed using cutting edge technology under sterile conditions then used as a treatment the same day in office as a minor office procedure.

These cell-based therapies can potentially repair and regenerate the damaged tissues, resulting in relief of pain and improvement in mobility and function. Stem cell therapy should be considered in cases of osteoarthritis, ligament/tendon damage, and cartilage injury.

Allogenic stem cells—meaning not from your body—are derived most often from donated umbilical cord, placenta and/or amniotic stem cells. These are stem cells from a bottle. There is a lot of debate about the efficacy between autologous and umbilical/placenta and/or amniotic stem cells.

An important point regarding the use of umbilical/placenta and/or amniotic stem cells is that there are no live, FDA approved, umbilical/placenta and/or amniotic stem cell products allowed or available for orthopedic use. If a provider or clinic claims to be using FDA approved live donor stem cells I would ask more questions regarding the FDA guidelines of specific regulations of human cells, tissues, and cellular and tissue-based products.

Your Own Cells Are Better

Stem cells from elderly donors do not have as much pluripotential as cells from younger donors. Nevertheless, these cells are capable of self-renewal and differentiation into osteoblasts, chondroblasts, adipocytes and other cell lineages
Despite controversial reports, the general consensus supports that stem cell proliferation rate is lower in the elderly, but their activity is sufficient for growth and self-renewal.
No risk at all of provoking immune reactions using your own cells.
No risk of contamination and spreading of communicable disease using your own cells.
Umbilical cord stem cells or amniotic stem cells in a bottle are not live. If there were live cells they would not be FDA approved products.

3. Prolotherapy

Comprehensive prolotherapy utilizes various types of injections to induce an inflammatory reaction in order to mimic an injury and bring the body’s own immune cells and healing factors to repair and rebuild injured and degenerated soft tissue.

Prolotherapy stimulates an immune response that signals fibroblasts, growth factors, collagen-building precursors, and stem cells to an injured area. In turn, this helps with reinforcing connective tissue resulting in ligament/tendon thickening and stability. This therapy is used for chronic myofascial pain, back pain, osteoarthritis, and ligament/tendon injuries. Prolotherapy is also a great treatment for hypermobile tendons and ligaments that have a tendency towards strains and sprains. Ligamentous instability often results in areas feeling tighter or having increased pain in the area. Our muscles tighten in order to compensate for the instability. If healing does not occur as the injury or instability continue our body will try to stabilize by increasing calcium deposits leading to bone spurs or osteoarthritis

4. Platelet Rich Plasma (PRP)

Platelet-rich plasma therapy involves using your own blood plasma and platelets as an enriched source of growth factors and immune cells. This concentrated source of platelets, growth factors, and immune cells stimulate healing of bone and soft tissue.

Our bodies are constantly trying to find equilibrium between the breakdown and regeneration of tissues. When we have an injury to a tissue or repeated stress on a joint resulting in osteoarthritis, tendinopathies, or rotator cuff injuries more emphasis is put on breakdown than repair and equilibrium is lost.

The goal of using regenerative medicine such as platelet-rich plasma therapy is to shift the equilibrium back towards regeneration by helping the body repair and heal itself.

This therapy can be utilized for minor tearing of ligaments and tendons, osteoarthritis, plantar fasciitis, ligament instability, and overuse injuries.

A PRP or Platelet Rich Plasma aesthetics is a remarkable and new non-surgical approach to facial skin rejuvenation and hair restoration. PRP is an organic plasma with a concentration of platelets taken from one’s own blood and is an enriched source of growth factors. Your own blood is concentrated to create a plasma rich in growth factors.

The PRP is taken and applied to the face using a microneedling technique to stimulate growth and repair. The growth factors do the work to regenerate dry and aged skin. PRP promotes the formation of healthy collagen and the deposit of elastic tissue.

The PRP can also be taken and applied to the scalp to stimulate “new” and “denser” hair growth. There are over 30 growth factors in PRP that repair blood vessel damage, skin damage, and provide nutrition to the cells in the scalp. PRP promotes new blood supply to hair follicles and reduces inflammation of the scalp creating healthy, productive hair follicles.

5. Perineural Injection Therapy (PIT)

Perineural injection therapy specifically targets neuropathic pain and neurogenic inflammation meaning the nerve fiber itself is damaged, injured, or chronically inflamed. This type of pain often develops after an injury and is usually chronic, unrelenting, and diffuse in nature. The quality of pain is often aching, nagging, or burning with fluctuating severity.

The therapy involves superficial injections of dextrose along cutaneous nerve pathways. Injections of dextrose correct glycopenia (decreased glucose/energy), restoring energy balance, and it raises pH, creating a more neutral environment and restoring tissue physiology. The dextrose also opens ion-gated channels to decrease nerve signaling, which calms down the inflammation around the nerve allowing time for the nerve to heal. These injections are also used to treat conditions such as peripheral neuropathy. Dextrose which is a form of glucose is extremely safe and widely used as an injectable and as an IV solution. There is minimal risk of infection or adverse reaction with the subcutaneous injection and there have been no allergic reactions observed.

6. Prolozone

Prolozone uses a combination of a prolotherapy dextrose based solution and ozone/oxygen gas into degenerated or injured joints, and areas of pain.

Ozone works by improving oxygen utilization in a localized area of damaged connective tissue and improving signaling of immune cells and growth factors to areas of injury. Ozone helps to improve healing and restore full function.

7. Trigger Point Injection

Trigger points are tight, sore areas in muscle tissue that are caused by trauma or injury, strains/sprains, chronic overwork, and poor posture.

They can result in discomfort and pain, muscle spasm, decreased range of motion, and can aggravate tension headaches, vertebral disc issues, pull vertebrae out of alignment and leave you prone to further injury by encouraging you to favor another area of your body.

Trigger point injection therapy is a minimally invasive injection technique that uses homeopathic products and anesthetic to release areas of acute and chronic tension and pain.

8. Shockwave / Acoustic Compression Therapy

Heal pain faster, reduce pain meds, and restore improved mobility with a non-invasive treatment to trigger your body’s own healing processes in a short therapy time of only 15-30 minutes.

Shockwave/Acoustic Compression Therapy uses precision applied sound waves to trigger your body to respond to the targeted area.

The nature of the therapy and the equipment we use enables us to pin-point the treatment directly to the source of pain or reduced mobility, for both a more effective and more targeted solution. This therapy allows us to target and treat both shallow and deep sources triggering your pain or stiffness.

It is applicable to any area of the body, including muscles, tendons, and joints.

Dr. Squires uses this innovative therapy to treat injured areas causing both acute and chronic pain by:

Improving range of motion
Reducing pain, stiffness, and chronic inflammation
Improving circulation that helps faster healing
Stimulating collagen production
Signaling stem cell and growth factors
Helping you get back to your daily activities with a completely outpatient treatment

Shockwave therapy, also known as Myofascial Acoustic Compression Therapy, uses sound (acoustic) waves to trigger biochemical changes in living tissue.

Mechanical forces induce a wide range of cellular events, including cell proliferation, differentiation, gene expression and protein synthesis of connective tissue components. They also signal production of cytokines (protein messengers), growth factors and stem cells to the injured area.

But not all pain actually starts from where it feels like the pain is emanating from. So part of the process can include discovering the true source of the pain so that the root of the pain is targeted and resolved.

Dr. Squires uses the PiezoWave2 device and her medical experience to root out the source of your pain, and heal it with targeted application of these acoustic waves.

She uses your feedback during the treatment to identify the source and heal it, so you can get back to your normal life activities without the use of surgery or medications.

One of the advantages of ShockWave/Acoustic Compression Therapy is that it is a non-invasive, quick, and targeted therapy.

Sessions are as short as 15-30 minutes.

Normally, treatments are performed 1-2 times per week as part of your treatment plan that can vary depending on the nature of the pain and whether it is an acute or chronic condition.

3-6 treatments may be needed to achieve significant improvements.

9. Advanced Therapies for Acute Injury and Osteoarthritis (A2M)

Alpha 2 Macroglobulin, or A2M is a concentrated protein injection therapy cultivated from your own plasma. A2M uses proven scientific techniques and natural healing methods to successfully treat in the early intervention of acute musculoskeletal injuries and osteoarthritis at its source by modulating cartilage-degrading enzymes to prevent cartilage breakdown. Once the signals for breakdown are inhibited, messengers and growth factors such as platelet derived growth factor (PDGF) and nerve growth factor (NGF) are activated, promoting tissue growth and supporting the overall restoration of the affected joint.

Scientific evidence points to A2M as the key to stopping osteoarthritis at the molecular level. A2M is a Broad Spectrum Multi-Purpose Protease Inhibitor (powerful chemical in destroying proteins that cause arthritis) that captures and inactivates the three major chemicals that lead to joint breakdown and cartilage damage. Alpha-2-macroglobulin’s ability to generally inhibit proteases both in chronic and neuropathic pains and inflammatory joint problems provide relief of symptoms while promoting the body’s innate ability to heal. Reference: Wang S, Wei X, Zhou J, Zhang J, Li K, Chen Q, Terek R, Fleming BC, Goldring MB, Ehrlich MG, Zhang G, Wei L. Identification of α2-macroglobulin as a master inhibitor of cartilage-degrading factors that attenuates the progression of posttraumatic osteoarthritis. Arthritis Rheumatol. 2014 Jul;66(7):1843-53. doi: 10.1002/art.38576. PMID: 24578232; PMCID: PMC4187342. Montesano PX, Cuellar JM,(2017) Scuderi GJ. Intradiscal injection of an autologous alpha-2-macroglobulin concentrate alleviates back pain in FAC-positive patients. Ortho & Rheuma. ; 4(2): 555634. Demirag B, Sarisozen B, Ozer O, Kaplan T, Ozturk C. Enhancement of tendon-bone healing of anterior cruciate ligament grafts by blockage of matrix metalloproteinases. J Bone Joint Surg Am. 2005 Nov;87(11):2401-10. doi: 10.2106/JBJS.D.01952. PMID: 16264114.

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Regenerative Therapies for Pain Relief and Longevity

Heal pain faster, reduce pain meds, and restore improved mobility with a non-invasive treatment to trigger your body’s own healing processes in a short therapy time of only 15-30 minutes.

Regenerative Therapies for
Pain Relief and Longevity